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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1598328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ngf
Name: nerve growth factor
Acc ID: CHEBI:84116
Term: triprolidine
Definition: An N-alkylpyrrolidine that is acrivastine in which the pyridine ring is lacking the propenoic acid substituent. It is a sedating antihistamine that is used (generally as the monohydrochloride monohydrate) for the relief of the symptoms of uticaria, rhinitis, and various pruritic skin disorders.
Chemical ID: MESH:D014311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ngfmultiple interactionsEXP 6480464CTDTriprolidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]PMID:15167971
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