Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593265
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atm
Name: ATM serine/threonine kinase
Acc ID: CHEBI:78671
Term: sodium chromate
Definition: An inorganic sodium salt consisting of sodium and chromate ions in a 2:1 ratio.
Chemical ID: MESH:C028982
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atmdecreases expressionISOATM (Homo sapiens)6480464CTDsodium chromate(VI) results in decreased expression of ATM protein modified formPMID:28318385
Atmmultiple interactionsISOAtm (Mus musculus)6480464CTD[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein; Melatonin inhibits the reaction [[sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of ATM protein]PMID:35643323
Atmmultiple interactionsISOATM (Homo sapiens)6480464CTDMUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in decreased expression of ATM protein modified form]PMID:28318385
Go Back to source page   Continue to Ontology report