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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt2A
Name: metallothionein 2A
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt2Adecreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of MT2A mRNAPMID:15890375 PMID:19162173
Mt2Aaffects expressionISOMt2 (Mus musculus)6480464CTDpirinixic acid affects the expression of MT2 mRNAPMID:11798191 PMID:19850644
Mt2Adecreases expressionISOMt2 (Mus musculus)6480464CTDpirinixic acid results in decreased expression of MT2 mRNAPMID:17321000 PMID:20059764 PMID:20813756
Mt2Aincreases expressionISOMt2 (Mus musculus)6480464CTDpirinixic acid results in increased expression of MT2 mRNAPMID:17426115 PMID:18301758 PMID:18445702 PMID:23811191
Mt2Amultiple interactionsISOMt2 (Mus musculus)6480464CTDpirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MT2 mRNA]; PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MT2 mRNA]]; PPARA protein affects the reaction [pirinixic acid results in decreased expression of MT2 mRNA]; PPARA protein promotes the reaction [pirinixic acid results in decreased expression of MT2 mRNA]PMID:17321000 PMID:19850644 PMID:20059764 PMID:27853831
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