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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs16
Name: regulator of G-protein signaling 16
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs16increases expressionISORgs16 (Mus musculus)6480464CTDValproic Acid results in increased expression of RGS16 mRNAPMID:27645313
Rgs16increases expressionISORGS16 (Homo sapiens)6480464CTDValproic Acid results in increased expression of RGS16 mRNAPMID:23179753 PMID:24935251
Rgs16multiple interactionsISORgs16 (Mus musculus)6480464CTDKDM1A protein affects the reaction [Valproic Acid inhibits the reaction [Dexamethasone results in decreased expression of RGS16 mRNA]]; Valproic Acid inhibits the reaction [Dexamethasone results in decreased expression of RGS16 mRNA]PMID:27645313
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