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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563607
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cenpa
Name: centromere protein A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cenpadecreases expressionISOCENPA (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of CENPA mRNAPMID:20064835 PMID:21802500 PMID:26238291
Cenpadecreases expressionISOCenpa (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CENPA proteinPMID:29145655
Cenpadecreases methylationISOCENPA (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of CENPA promoterPMID:27901495
Cenpadecreases methylationISOCenpa (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of CENPA promoterPMID:27901495
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