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GENE - TERM ANNOTATION REPORT

RGD ID: 1562602
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pml
Name: PML nuclear body scaffold
Acc ID: GO:0008630
Term: intrinsic apoptotic signaling pathway in response to DNA damage
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
Definition Source(s): GOC:go_curators, GOC:mtg_apoptosis
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmlacts_upstream_of_or_withinISOPml (Mus musculus)1624291RGDMGI:104662 MGI:2429949 PMID:15626733 PMID:9806545

PMID:15626733 PMID:9806545
Pmlinvolved_inISOPML (Homo sapiens) and UniProtKB:P29590-51624291RGD PMID:12402044

PMID:12402044
Pmlinvolved_inIBAMGI:104662 or PANTHER:PTN0086190911600115GO_CentralGO_REF:0000033

GO_REF:0000033
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