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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561632
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il25
Name: interleukin 25
Acc ID: CHEBI:164200
Term: triclosan
Definition: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Chemical ID: MESH:D014260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il25decreases expressionISOIL25 (Homo sapiens)6480464CTDTriclosan results in decreased expression of IL25 mRNAPMID:30510588
Il25decreases expressionISOIl25 (Mus musculus)6480464CTDTriclosan results in decreased expression of IL25 proteinPMID:26048654
Il25multiple interactionsISOIL25 (Homo sapiens)6480464CTDTriclosan inhibits the reaction [Lipopolysaccharides results in increased expression of IL25 mRNA]PMID:20507366
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