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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558600
Species: Mus musculus
RGD Object: Gene
Symbol: Ern1
Name: endoplasmic reticulum to nucleus signalling 1
Acc ID: CHEBI:31941
Term: oxaliplatin
Definition: A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Chemical ID: MESH:C030110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ern1increases expressionISOErn1 (Rattus norvegicus)6480464CTDOxaliplatin results in increased expression of ERN1 mRNAPMID:32544411 PMID:38037725
Ern1multiple interactionsISOErn1 (Rattus norvegicus)6480464CTDLycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA]; naringin inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA]PMID:32544411 PMID:38037725
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