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GENE - TERM ANNOTATION REPORT

RGD ID: 1558100
Species: Mus musculus
RGD Object: Gene
Symbol: Rspo2
Name: R-spondin 2
Acc ID: GO:0090263
Term: positive regulation of canonical Wnt signaling pathway
Definition: Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Definition Source(s): GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rspo2acts_upstream_of_or_withinIDA 2290270MGI PMID:18256198 PMID:19213727

PMID:18256198 PMID:19213727
Rspo2acts_upstream_of_or_withinIGIMGI:12982182290270MGI PMID:18256198

PMID:18256198
Rspo2acts_upstream_of_or_withinIMPMGI:30459652290270MGI PMID:18256198

PMID:18256198
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