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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557355
Species: Mus musculus
RGD Object: Gene
Symbol: Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Acc ID: CHEBI:29042
Term: alpha-D-glucose 1-phosphate
Definition: A D-glucopyranose 1-phosphate in which the anomeric centre has alpha-configuration.
Chemical ID: MESH:C031590
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Idh2increases abundanceEXP 6480464CTDIDH2 protein mutant form results in increased abundance of glucose-1-phosphatePMID:27469509
Idh2multiple interactionsEXP 6480464CTDTriazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glucose-1-phosphate]PMID:27469509
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