GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adipoq | affects response to substance | EXP | | 6480464 | CTD | ADIPOQ protein affects the susceptibility to Ozone | PMID:23755285 | Adipoq | decreases expression | EXP | | 6480464 | CTD | Ozone results in decreased expression of ADIPOQ mRNA | PMID:12763052 | Adipoq | multiple interactions | EXP | | 6480464 | CTD | [ADIPOQ protein binds to CDH13 protein] inhibits the reaction [Ozone results in increased expression of IL17A mRNA]; [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ADIPOQ mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of ADIPOQ protein; ADIPOQ gene mutant form promotes the reaction [Ozone results in increased expression of IL17A mRNA]; ADIPOQ gene mutant form promotes the reaction [Ozone results in increased expression of SAA3 mRNA]; ADIPOQ protein inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of CXCL1 protein]; ADIPOQ protein inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL1RN protein]; ADIPOQ protein inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL6 protein]; ADIPOQ protein inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of TNF protein] | PMID:22474022 PMID:23755285 PMID:34911549 | Adipoq | increases expression | ISO | Adipoq (Rattus norvegicus) | 6480464 | CTD | Ozone results in increased expression of ADIPOQ | PMID:24103449 | Adipoq | multiple interactions | ISO | Adipoq (Rattus norvegicus) | 6480464 | CTD | [Ozone co-treated with Particulate Matter] results in decreased expression of ADIPOQ mRNA; [Particulate Matter co-treated with Ozone] promotes the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; Ozone promotes the reaction [Fructose results in decreased expression of ADIPOQ mRNA] | PMID:23968387 | | ||||||||||||||||||||||
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