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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551410
Species: Mus musculus
RGD Object: Gene
Symbol: Exoc8
Name: exocyst complex component 8
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Exoc8decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of EXOC8 promoterPMID:27312807
Exoc8decreases expressionISOEXOC8 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of EXOC8 proteinPMID:34186270
Exoc8decreases expressionISOExoc8 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of EXOC8 mRNAPMID:25181051
Exoc8increases expressionISOExoc8 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of EXOC8 mRNAPMID:34947998
Exoc8increases methylationISOExoc8 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of EXOC8 genePMID:28505145
Exoc8multiple interactionsISOEXOC8 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EXOC8 mRNAPMID:28628672
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