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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551392
Species: Mus musculus
RGD Object: Gene
Symbol: Mthfr
Name: methylenetetrahydrofolate reductase
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mthfrincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of MTHFR mRNAPMID:30357543
Mthfrdecreases expressionISOMTHFR (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of MTHFR mRNA; sodium arsenite results in decreased expression of MTHFR proteinPMID:19766132 PMID:30664189
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