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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550447
Species: Mus musculus
RGD Object: Gene
Symbol: Tmem106b
Name: transmembrane protein 106B
Acc ID: CHEBI:17823
Term: calcitriol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Chemical ID: MESH:D002117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tmem106bincreases expressionISOTMEM106B (Homo sapiens)6480464CTDCalcitriol results in increased expression of TMEM106B mRNAPMID:21592394
Tmem106bmultiple interactionsISOTMEM106B (Homo sapiens)6480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of TMEM106B mRNAPMID:21592394
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