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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550135
Species: Mus musculus
RGD Object: Gene
Symbol: Gjb2
Name: gap junction protein, beta 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gjb2multiple interactionsEXP 6480464CTDDiethylnitrosamine results in decreased expression of and affects the localization of GJB2 protein; mitoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of and affects the localization of GJB2 protein]PMID:36037915
Gjb2increases expressionISOGjb2 (Rattus norvegicus)6480464CTDDiethylnitrosamine results in increased expression of GJB2 mRNAPMID:19638242
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