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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trap1
Name: TNF receptor-associated protein 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trap1affects response to substanceISOTRAP1 (Homo sapiens)6480464CTDTRAP1 protein affects the susceptibility to Hydrogen PeroxidePMID:21366594
Trap1decreases response to substanceISOTRAP1 (Homo sapiens)6480464CTDTRAP1 protein results in decreased susceptibility to Hydrogen PeroxidePMID:17853063
Trap1increases expressionISOTRAP1 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of TRAP1 proteinPMID:21366594
Trap1multiple interactionsISOTRAP1 (Homo sapiens)6480464CTDPINK1 protein affects the reaction [Hydrogen Peroxide results in increased expression of TRAP1 protein]; TRAP1 protein affects the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; TRAP1 protein affects the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]PMID:21366594
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