Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acat2
Name: acetyl-CoA acetyltransferase 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acat2increases expressionEXP 6480464CTDValproic Acid results in increased expression of ACAT2 mRNAPMID:23665938
Acat2affects expressionISOACAT2 (Homo sapiens)6480464CTDValproic Acid affects the expression of ACAT2 mRNAPMID:25979313
Acat2affects expressionISOAcat2 (Mus musculus)6480464CTDValproic Acid affects the expression of ACAT2 mRNAPMID:17292431
Acat2decreases expressionISOACAT2 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ACAT2 mRNAPMID:19101580 PMID:23179753 PMID:27188386 PMID:28001369 PMID:29154799
Acat2multiple interactionsISOACAT2 (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of ACAT2 mRNAPMID:17183730
Go Back to source page   Continue to Ontology report