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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359266
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pmaip1
Name: phorbol-12-myristate-13-acetate-induced protein 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmaip1decreases expressionISOPmaip1 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of PMAIP1 mRNAPMID:37682722
Pmaip1increases expressionISOPMAIP1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of PMAIP1 mRNAPMID:29301061 PMID:38568856
Pmaip1increases expressionISOPmaip1 (Mus musculus)6480464CTDsodium arsenite results in increased expression of PMAIP1 mRNAPMID:16166651 PMID:20477944 PMID:20883709
Pmaip1multiple interactionsISOPmaip1 (Mus musculus)6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of PMAIP1 mRNA; TRP53 gene mutant form affects the reaction [sodium arsenite results in increased expression of PMAIP1 mRNA]; TRP53 protein affects the reaction [sodium arsenite results in increased expression of PMAIP1 mRNA]; TRP73 protein affects the reaction [sodium arsenite results in increased expression of PMAIP1 mRNA]PMID:16166651 PMID:20477944 PMID:34876320
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