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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359152
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl7
Name: C-C motif chemokine ligand 7
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl7increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of CCL7 mRNAPMID:35163327
Ccl7multiple interactionsEXP 6480464CTD[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CCL7 mRNAPMID:35163327
Ccl7decreases expressionISOCCL7 (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased expression of CCL7 mRNAPMID:32219433
Ccl7decreases secretionISOCCL7 (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased secretion of CCL7 proteinPMID:32219433
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