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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A4
Name: cytochrome P450 family 3 subfamily A member 4
Acc ID: CHEBI:9342
Term: sulfinpyrazone
Definition: A pyrazolidine that has formula C23H20N2O3S.
Chemical ID: MESH:D013442
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A4increases activityEXP 6480464CTDSulfinpyrazone results in increased activity of CYP3A4 proteinPMID:12065438 PMID:9512926
CYP3A4increases expressionEXP 6480464CTDSulfinpyrazone results in increased expression of CYP3A4 mRNAPMID:10219967 PMID:16837568 PMID:17954527
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