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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A4
Name: cytochrome P450 family 3 subfamily A member 4
Acc ID: CHEBI:6773
Term: Mesaconitine
Definition: A diterpenoid that has formula C33H45NO11.
Chemical ID: MESH:C019470
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A4increases expressionEXP 6480464CTDmesaconitine results in increased expression of CYP3A4 mRNAPMID:30303438
CYP3A4multiple interactionsEXP 6480464CTD[Aconitine co-treated with mesaconitine co-treated with hypaconitine] results in increased expression of CYP3A4 mRNAPMID:30303438
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