Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1352962
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	CYP3A4
Name:	cytochrome P450 family 3 subfamily A member 4

Acc ID:	CHEBI:6413
Term:	letrozole
Definition:	A triazole that has formula C17H11N5.
Chemical ID:	MESH:C067431

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
CYP3A4	increases oxidation	EXP		6480464	CTD	CYP3A4 protein results in increased oxidation of letrozole	PMID:19845430

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.