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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A4
Name: cytochrome P450 family 3 subfamily A member 4
Acc ID: CHEBI:135048
Term: dimemorfan
Definition: null
Chemical ID: MESH:C012621
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A4increases oxidationEXP 6480464CTDCYP3A4 protein results in increased oxidation of dimemorfanPMID:19593786
CYP3A4multiple interactionsEXP 6480464CTDKetoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of dimemorfan]PMID:19593786
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