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GENE - TERM ANNOTATION REPORT

RGD ID: 1351789
Species: Homo sapiens
RGD Object: Gene
Symbol: RAB7A
Name: RAB7A, member RAS oncogene family
Acc ID: GO:0005770
Term: late endosome
Definition: A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
Definition Source(s): NIF_Subcellular:nlx_subcell_20090702, PMID:11964142, PMID:2557062
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RAB7A ISORab7a (Rattus norvegicus)9068941RGD PMID:19337031 REF_RGD_ID:4892338
RAB7Alocated_inIEAUniProtKB:P09527 or UniProtKB:P51150 or ensembl:ENSMUSP00000109230 or ensembl:ENSRNOP00000016432150520179Ensembl GO_REF:0000107
RAB7Ais_active_inIBAFB:FBgn0015795 or FB:FBgn0032782 or MGI:105068 or MGI:2442295 or PANTHER:PTN000635769 or Rab7a (Rattus norvegicus) or UniProtKB:P51151 or UniProtKB:Q96AH8 or WB:WBGene00004271 or ZFIN:ZDB-GENE-040426-1352150520179GO_Central GO_REF:0000033
RAB7Alocated_inIDA 150520179MGI PMID:14617358 PMID:15078902 PMID:17010938 PMID:18272684

PMID:14617358 PMID:15078902 PMID:17010938 PMID:18272684
RAB7Alocated_inTAS 150520179PINC PMID:2115402

PMID:2115402
RAB7Alocated_inIEAPANTHER:PTHR47981:SF13150520179TreeGrafter GO_REF:0000118
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