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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350223
Species: Homo sapiens
RGD Object: Gene
Symbol: MAP1LC3B
Name: microtubule associated protein 1 light chain 3 beta
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAP1LC3Baffects expressionEXP 6480464CTDtrichostatin A affects the expression of MAP1LC3B mRNAPMID:28542535
MAP1LC3Baffects localizationEXP 6480464CTDtrichostatin A affects the localization of MAP1LC3B protein modified formPMID:20543569
MAP1LC3Bincreases cleavageEXP 6480464CTDtrichostatin A results in increased cleavage of MAP1LC3B proteinPMID:20543569
MAP1LC3Bincreases expressionEXP 6480464CTDtrichostatin A results in increased expression of MAP1LC3B mRNA; trichostatin A results in increased expression of MAP1LC3B protein modified formPMID:19606018 PMID:20962572
MAP1LC3Bincreases expressionISOMap1lc3b (Mus musculus)6480464CTDtrichostatin A results in increased expression of MAP1LC3B protein modified formPMID:29476062
MAP1LC3Bincreases expressionISOMap1lc3b (Rattus norvegicus)6480464CTDtrichostatin A results in increased expression of MAP1LC3B protein modified formPMID:29476062
MAP1LC3Bmultiple interactionsISOMap1lc3b (Mus musculus)6480464CTDATG7 gene mutant form inhibits the reaction [trichostatin A promotes the reaction [Cisplatin results in increased expression of MAP1LC3B protein modified form]]; ATG7 gene mutant form inhibits the reaction [trichostatin A results in increased expression of MAP1LC3B protein modified form]; trichostatin A promotes the reaction [Cisplatin results in increased expression of MAP1LC3B protein modified form]PMID:29476062
MAP1LC3Bmultiple interactionsISOMap1lc3b (Rattus norvegicus)6480464CTDChloroquine promotes the reaction [trichostatin A results in increased expression of MAP1LC3B protein modified form]PMID:29476062
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