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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349666
Species: Homo sapiens
RGD Object: Gene
Symbol: ENPP5
Name: ectonucleotide pyrophosphatase/phosphodiesterase family member 5
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ENPP5decreases expressionISOEnpp5 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ENPP5 mRNAPMID:30816183 PMID:32145629 PMID:32528016
ENPP5decreases expressionISOEnpp5 (Mus musculus)6480464CTDbisphenol A results in decreased expression of ENPP5 proteinPMID:35999755
ENPP5increases expressionISOEnpp5 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ENPP5 mRNAPMID:34947998
ENPP5increases methylationISOEnpp5 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of ENPP5 genePMID:28505145
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