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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349531
Species: Homo sapiens
RGD Object: Gene
Symbol: S100A8
Name: S100 calcium binding protein A8
Acc ID: CHEBI:5615
Term: halothane
Definition: A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position.
Chemical ID: MESH:D006221
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100A8increases expressionEXP 6480464CTDHalothane results in increased expression of S100A8 mRNAPMID:28138970
S100A8increases expressionISOS100a8 (Mus musculus)6480464CTDHalothane results in increased expression of S100A8 mRNAPMID:24747151 PMID:32795494
S100A8multiple interactionsISOS100a8 (Mus musculus)6480464CTDDantrolene inhibits the reaction [Halothane results in increased expression of S100A8 mRNA]; Ryanodine promotes the reaction [Halothane results in increased expression of S100A8 mRNA]PMID:32795494
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