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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348013
Species: Homo sapiens
RGD Object: Gene
Symbol: HMGA2
Name: high mobility group AT-hook 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMGA2affects expressionEXP 6480464CTDValproic Acid affects the expression of HMGA2 mRNAPMID:25979313
HMGA2decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of HMGA2 mRNAPMID:23179753 PMID:28001369
HMGA2increases expressionEXP 6480464CTDValproic Acid results in increased expression of HMGA2 mRNAPMID:23179753 PMID:26272509
HMGA2multiple interactionsEXP 6480464CTD[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HMGA2 mRNAPMID:27188386
HMGA2decreases expressionISOHmga2 (Mus musculus)6480464CTDValproic Acid results in decreased expression of HMGA2 mRNAPMID:19136453 PMID:20546886
HMGA2increases expressionISOHmga2 (Mus musculus)6480464CTDValproic Acid results in increased expression of HMGA2 mRNAPMID:24896083
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