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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347215
Species: Homo sapiens
RGD Object: Gene
Symbol: TIMP1
Name: TIMP metallopeptidase inhibitor 1
Acc ID: CHEBI:20993
Term: aldehydo-D-glucosamine
Definition: The open-chain form of D-glucosamine.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TIMP1increases expressionISOTimp1 (Rattus norvegicus)6480464CTDGlucosamine results in increased expression of TIMP1 mRNAPMID:17109745
TIMP1multiple interactionsISOTimp1 (Rattus norvegicus)6480464CTDGlucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA]PMID:17109745
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