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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345345
Species: Homo sapiens
RGD Object: Gene
Symbol: MIR141
Name: microRNA 141
Acc ID: CHEBI:9513
Term: thalidomide
Definition: A racemate comprising equimolar amounts of R- and S-thalidomide.
Chemical ID: MESH:D013792
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR141multiple interactionsISOMir141 (Rattus norvegicus)6480464CTDMIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of BAX protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of FGF2 protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of IL6 protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF protein]]; Thalidomide inhibits the reaction [Paraquat results in decreased expression of MIR141]PMID:33015978
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