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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345007
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2E1decreases activityISOCyp2e1 (Rattus norvegicus)6480464CTDDextran Sulfate results in decreased activity of CYP2E1 proteinPMID:28438436
CYP2E1multiple interactionsISOCyp2e1 (Rattus norvegicus)6480464CTD[Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazonePMID:28438436
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