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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344082
Species: Homo sapiens
RGD Object: Gene
Symbol: SERPING1
Name: serpin family G member 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SERPING1affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of SERPING1 promoterPMID:27901495
SERPING1decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of SERPING1 exonPMID:27901495
SERPING1increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of SERPING1 mRNAPMID:22316170
SERPING1decreases expressionISOSerping1 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SERPING1 mRNAPMID:19770486
SERPING1increases expressionISOSerping1 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of SERPING1 mRNAPMID:22228805
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