GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GDF15 | decreases response to substance | EXP | | 6480464 | CTD | GDF15 protein results in decreased susceptibility to Indomethacin | PMID:22615612 | GDF15 | increases expression | EXP | | 6480464 | CTD | Indomethacin results in increased expression of GDF15 mRNA; Indomethacin results in increased expression of GDF15 protein | PMID:15180942 PMID:15509713 PMID:15555568 PMID:16984733 PMID:17401462 PMID:18076062 | GDF15 | multiple interactions | EXP | | 6480464 | CTD | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA | PMID:28628672 | GDF15 | increases expression | ISO | Gdf15 (Mus musculus) | 6480464 | CTD | Indomethacin results in increased expression of GDF15 mRNA | PMID:18076062 | |
Go Back to source page | Continue to Ontology report |