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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343424
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2A6
Name: cytochrome P450 family 2 subfamily A member 6
Acc ID: CHEBI:48408
Term: ethyl vanillin
Definition: A member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group.
Chemical ID: MESH:C045941
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2A6decreases activityEXP 6480464CTDethyl vanillin results in decreased activity of CYP2A6 proteinPMID:32496054
CYP2A6multiple interactionsEXP 6480464CTD[[ethyl vanillin results in decreased activity of CYP2A6 protein] which results in decreased hydroxylation of 3-cyanocoumarin] which results in decreased chemical synthesis of 3-cyano-7-hydroxycoumarin; [ethyl vanillin results in decreased activity of CYP2A6 protein] which results in decreased hydroxylation of 3-cyanocoumarinPMID:32496054
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