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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332548
Species: Mus musculus
RGD Object: Gene
Symbol: Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Acc ID: CHEBI:4811
Term: epoxiconazole
Definition: A racemate composed of equimolar amounts of (2S,3R)- and (2R,3S)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms.
Chemical ID: MESH:C109476
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1aincreases expressionEXP 6480464CTDepoxiconazole results in increased expression of PPARGC1A mRNAPMID:35436446
Ppargc1aincreases expressionISOPpargc1a (Rattus norvegicus)6480464CTDepoxiconazole results in increased expression of PPARGC1A mRNAPMID:29038839
Ppargc1amultiple interactionsISOPpargc1a (Rattus norvegicus)6480464CTD[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of PPARGC1A mRNA; [cyproconazole co-treated with epoxiconazole] results in increased expression of PPARGC1A mRNAPMID:29038839
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