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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332548
Species: Mus musculus
RGD Object: Gene
Symbol: Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Acc ID: CHEBI:38728
Term: monocrotophos
Definition: An alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate.
Chemical ID: MESH:D008999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1adecreases expressionISOPpargc1a (Rattus norvegicus)6480464CTDMonocrotophos results in decreased expression of PPARGC1A mRNAPMID:35403558
Ppargc1amultiple interactionsISOPpargc1a (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of PPARGC1A mRNA]PMID:35403558
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