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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332548
Species: Mus musculus
RGD Object: Gene
Symbol: Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1aaffects expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARGC1A mRNAPMID:37080397
Ppargc1adecreases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1A proteinPMID:39197524
Ppargc1amultiple interactionsEXP 6480464CTD[Palm Oil analog co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARGC1A mRNA; [Palm Oil analog co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARGC1A protein; [Palm Oil co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARGC1A proteinPMID:39197524
Ppargc1adecreases expressionISOPpargc1a (Rattus norvegicus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1A mRNAPMID:27509375
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