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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332039
Species: Mus musculus
RGD Object: Gene
Symbol: Bace1
Name: beta-site APP cleaving enzyme 1
Acc ID: CHEBI:87639
Term: azure B
Definition: An organic chloride salt having 3-(dimethylamino)-7-(methylamino)phenothiazin-5-ium as the counterion. It is used in making azure eosin stains for blood smear staining and is an active metabolite of methylene blue.
Chemical ID: MESH:C025819
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bace1decreases activityISOBACE1 (Homo sapiens)6480464CTDAzure B results in decreased activity of BACE1 proteinPMID:30500345
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