GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tet2 | decreases expression | ISO | TET2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of TET2 protein | PMID:33388378 | Tet2 | increases expression | ISO | TET2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of TET2 mRNA | PMID:29175454 PMID:38568856 | Tet2 | multiple interactions | ISO | TET2 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TET2 protein]; sodium arsenite affects the reaction [CTCF protein binds to TET2 promoter]; TET1 protein inhibits the reaction [sodium arsenite results in decreased expression of TET2 protein]; TET2 protein inhibits the reaction [sodium arsenite results in decreased expression of GSTP1 protein]; TET2 protein inhibits the reaction [sodium arsenite results in decreased expression of OGG1 protein]; TET2 protein inhibits the reaction [sodium arsenite results in decreased expression of TDG protein]; TET2 protein inhibits the reaction [sodium arsenite results in decreased expression of TET1 protein]; TET2 protein inhibits the reaction [sodium arsenite results in increased methylation of GSTP1 promoter]; TET2 protein inhibits the reaction [sodium arsenite results in increased methylation of OGG1 promoter] | PMID:29175454 PMID:33388378 | | ||||||||||||||||||||||
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