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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323180
Species: Mus musculus
RGD Object: Gene
Symbol: Tet2
Name: tet methylcytosine dioxygenase 2
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tet2increases expressionEXP 6480464CTDDoxorubicin results in increased expression of TET2 mRNAPMID:25896364
Tet2decreases expressionISOTET2 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of TET2 mRNAPMID:29803840
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