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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322470
Species: Mus musculus
RGD Object: Gene
Symbol: Alox12
Name: arachidonate 12-lipoxygenase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alox12decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ALOX12 mRNA; bisphenol A results in decreased expression of ALOX12 proteinPMID:26063408 PMID:35999755
Alox12decreases expressionISOAlox12 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ALOX12 mRNAPMID:26141625 PMID:30816183
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