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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322378
Species: Mus musculus
RGD Object: Gene
Symbol: Cda
Name: cytidine deaminase
Acc ID: CHEBI:28830
Term: chlorambucil
Definition: A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Chemical ID: MESH:D002699
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdadecreases response to substanceISOCDA (Homo sapiens)6480464CTDCDA protein results in decreased susceptibility to ChlorambucilPMID:10830723
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