GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SIRT4 | multiple interactions | ISO | Sirt4 (Rattus norvegicus) | 6480464 | CTD | Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in decreased expression of SQSTM1 protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in decreased phosphorylation of MTOR protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased lipidation of MAP1LC3B protein]] | PMID:35134463 | SIRT4 | multiple interactions | ISO | Sirt4 (Mus musculus) | 6480464 | CTD | Sirolimus affects the reaction [SIRT4 protein affects the reaction [Doxorubicin affects the expression of SQSTM1 protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in decreased phosphorylation of MTOR protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BAX protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased lipidation of MAP1LC3B protein]] | PMID:35134463 | |
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