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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320331
Species: Mus musculus
RGD Object: Gene
Symbol: Hdac1
Name: histone deacetylase 1
Acc ID: CHEBI:2679
Term: amphetamine
Definition: A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Chemical ID: MESH:D000661
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac1multiple interactionsEXP 6480464CTDHDAC1 gene mutant form promotes the reaction [Amphetamine results in increased expression of FOS mRNA]PMID:18632938
Hdac1multiple interactionsISOHdac1 (Rattus norvegicus)6480464CTDAmphetamine promotes the reaction [HDAC1 protein binds to FOS promoter]PMID:18632938
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