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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319733
Species: Mus musculus
RGD Object: Gene
Symbol: Gpr35
Name: G protein-coupled receptor 35
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpr35increases expressionISOGPR35 (Homo sapiens)6480464CTDQuercetin results in increased expression of GPR35 mRNAPMID:21632981
Gpr35multiple interactionsISOGpr35 (Rattus norvegicus)6480464CTDQuercetin binds to and results in increased activity of GPR35 proteinPMID:20919992
Gpr35multiple interactionsISOGPR35 (Homo sapiens)6480464CTDQuercetin binds to and results in increased activity of GPR35 proteinPMID:20919992
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