![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1319733 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of GPR35 mRNA | CTD | PMID:22206623 | 1,4-dihydroxy-2-naphthoic acid | multiple interactions | ISO | RGD:1319732 | 6480464 | 1, 4-dihydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1319733 | 6480464 | Ethinyl Estradiol affects the expression of GPR35 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1319733 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPR35 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1319733 | 6480464 | Ethinyl Estradiol results in increased expression of GPR35 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GPR35 mRNA | CTD | PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GPR35 mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1319733 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPR35 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1319733 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GPR35 mRNA | CTD | PMID:23994337 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1319733 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GPR35 mRNA | CTD | PMID:15652763 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | ISO | RGD:1319733 | 6480464 | 3 more ... | CTD | PMID:23994337 | 3-Hydroxy-2-naphthoate | multiple interactions | ISO | RGD:1319732 | 6480464 | 3-hydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1319733 | 6480464 | Fenretinide results in decreased expression of GPR35 mRNA | CTD | PMID:28973697 | 5-fluorouracil | affects response to substance | ISO | RGD:1319732 | 6480464 | GPR35 protein affects the susceptibility to Fluorouracil | CTD | PMID:15331170 | 5-fluorouracil | increases expression | ISO | RGD:1319732 | 6480464 | Fluorouracil results in increased expression of GPR35 mRNA | CTD | PMID:15331170 | 5-Nitro-2-(3-phenylpropylamino)benzoic acid | multiple interactions | ISO | RGD:1319732 | 6480464 | 5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of GPR35 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | ISO | RGD:1319732 | 6480464 | Acrylamide results in increased expression of GPR35 mRNA | CTD | PMID:32763439 | Aflatoxin B2 alpha | increases methylation | ISO | RGD:1319732 | 6480464 | aflatoxin B2 results in increased methylation of GPR35 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RGD:1319732 | 6480464 | Tretinoin results in increased expression of GPR35 mRNA | CTD | PMID:33167477 | aristolochic acid A | increases expression | ISO | RGD:1319732 | 6480464 | aristolochic acid I results in increased expression of GPR35 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases expression | ISO | RGD:1319732 | 6480464 | Benzo(a)pyrene results in increased expression of GPR35 mRNA | CTD | PMID:20064835, PMID:21632981 | benzo[a]pyrene | affects methylation | ISO | RGD:1319732 | 6480464 | Benzo(a)pyrene affects the methylation of GPR35 intron, Benzo(a)pyrene affects the methylation of GPR35 promoter | CTD | PMID:27901495, PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | RGD:1319732 | 6480464 | Benzo(a)pyrene results in increased methylation of GPR35 exon | CTD | PMID:27901495 | beta-naphthoflavone | increases expression | ISO | RGD:1319733 | 6480464 | beta-Naphthoflavone results in increased expression of GPR35 mRNA | CTD | PMID:23994337 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GPR35 mRNA | CTD | PMID:25181051 | buta-1,3-diene | decreases expression | ISO | RGD:1319733 | 6480464 | 1, 3-butadiene results in decreased expression of GPR35 mRNA | CTD | PMID:29038090 | carbon nanotube | increases expression | ISO | RGD:1319733 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | increases expression | ISO | RGD:1319732 | 6480464 | Cisplatin results in increased expression of GPR35 mRNA | CTD | PMID:27594783 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of GPR35 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of GPR35 mRNA | CTD | PMID:26033743 | copper(II) sulfate | decreases expression | ISO | RGD:1319732 | 6480464 | Copper Sulfate results in decreased expression of GPR35 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases methylation | ISO | RGD:1319732 | 6480464 | Cyclosporine results in decreased methylation of GPR35 promoter | CTD | PMID:27989131 | diazinon | increases methylation | ISO | RGD:1319732 | 6480464 | Diazinon results in increased methylation of GPR35 gene | CTD | PMID:22964155 | dicoumarol | multiple interactions | ISO | RGD:1319732 | 6480464 | Dicumarol binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | dicoumarol | multiple interactions | EXP | | 6480464 | Dicumarol binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | dioxygen | multiple interactions | ISO | RGD:1319733 | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GPR35 mRNA | CTD | PMID:30529165 | disodium cromoglycate | multiple interactions | ISO | RGD:1319733 | 6480464 | Cromolyn Sodium binds to and results in increased activity of GPR35 protein | CTD | PMID:22967846 | disodium cromoglycate | multiple interactions | ISO | RGD:1319732 | 6480464 | 2-hydroxy-4-(4-(5-(2-methyl-3-phenylprop-2-enylidene)-4-oxo-2-sulfanylidene-1 more ... | CTD | PMID:20919992, PMID:22967846 | disodium cromoglycate | affects localization | ISO | RGD:1319732 | 6480464 | Cromolyn Sodium affects the localization of GPR35 protein | CTD | PMID:22967846 | disodium cromoglycate | multiple interactions | EXP | | 6480464 | Cromolyn Sodium binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992, PMID:22967846 | ethanol | multiple interactions | ISO | RGD:1319733 | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GPR35 mRNA | CTD | PMID:30517762 | kynurenic acid | multiple interactions | ISO | RGD:1319732 | 6480464 | Kynurenic Acid binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425 | luteolin | multiple interactions | EXP | | 6480464 | Luteolin binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | luteolin | multiple interactions | ISO | RGD:1319732 | 6480464 | Luteolin binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | Niflumic acid | multiple interactions | ISO | RGD:1319732 | 6480464 | Niflumic Acid binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | Oxantel pamoate | multiple interactions | ISO | RGD:1319732 | 6480464 | oxantel pamoate binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425, PMID:20919992 | ozone | multiple interactions | ISO | RGD:1319733 | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of GPR35 mRNA | CTD | PMID:27106289 | paclitaxel | decreases response to substance | ISO | RGD:1319732 | 6480464 | GPR35 protein results in decreased susceptibility to Paclitaxel | CTD | PMID:16734730 | pamoic acid | multiple interactions | ISO | RGD:1319732 | 6480464 | 2-hydroxy-4-(4-(5-(2-methyl-3-phenylprop-2-enylidene)-4-oxo-2-sulfanylidene-1 more ... | CTD | PMID:20826425 more ... | pamoic acid | affects localization | ISO | RGD:1319732 | 6480464 | pamoic acid affects the localization of GPR35 protein | CTD | PMID:22967846 | pirinixic acid | multiple interactions | ISO | RGD:1319733 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GPR35 mRNA | CTD | PMID:19710929 | Pyrantel pamoate | multiple interactions | ISO | RGD:1319732 | 6480464 | Pyrantel Pamoate binds to and results in increased activity of GPR35 protein | CTD | PMID:20826425 | pyrvinium | multiple interactions | ISO | RGD:1319732 | 6480464 | pyrvinium binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | quercetin | increases expression | ISO | RGD:1319732 | 6480464 | Quercetin results in increased expression of GPR35 mRNA | CTD | PMID:21632981 | quercetin | multiple interactions | EXP | | 6480464 | Quercetin binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | quercetin | multiple interactions | ISO | RGD:1319732 | 6480464 | Quercetin binds to and results in increased activity of GPR35 protein | CTD | PMID:20919992 | tamoxifen | affects expression | ISO | RGD:1319733 | 6480464 | Tamoxifen affects the expression of GPR35 mRNA | CTD | PMID:17555576 | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GPR35 mRNA | CTD | PMID:32741896 | tetrachloromethane | multiple interactions | ISO | RGD:1319733 | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GPR35 mRNA | CTD | PMID:30517762 | titanium dioxide | increases expression | ISO | RGD:1319733 | 6480464 | titanium dioxide results in increased expression of GPR35 mRNA | CTD | PMID:29264374 | trovafloxacin | decreases expression | ISO | RGD:1319733 | 6480464 | trovafloxacin results in decreased expression of GPR35 mRNA | CTD | PMID:35537566 | valproic acid | increases methylation | ISO | RGD:1319732 | 6480464 | Valproic Acid results in increased methylation of GPR35 gene | CTD | PMID:29154799 | |