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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319531
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC7A11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC7A11affects expressionEXP 6480464CTDEstradiol affects the expression of SLC7A11 mRNAPMID:22574217
SLC7A11decreases expressionEXP 6480464CTDEstradiol results in decreased expression of SLC7A11 mRNAPMID:16474171 PMID:19167446
SLC7A11increases expressionEXP 6480464CTDEstradiol results in increased expression of SLC7A11 mRNAPMID:15159206 PMID:20106945 PMID:26198647 PMID:31614463 PMID:32234386 PMID:32387340
SLC7A11multiple interactionsEXP 6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of SLC7A11 mRNAPMID:30165855
SLC7A11multiple interactionsISOSlc7a11 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of SLC7A11 mRNAPMID:26496021
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