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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319235
Species: Homo sapiens
RGD Object: Gene
Symbol: C1R
Name: complement C1r
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C1Rdecreases expressionISOC1r (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in decreased expression of C1R mRNAPMID:19162173
C1Rdecreases expressionISOC1rb (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of C1R mRNAPMID:18467677
C1Rmultiple interactionsISOC1rb (Mus musculus)6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of C1R mRNA]PMID:18467677
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