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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319073
Species: Mus musculus
RGD Object: Gene
Symbol: Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Acc ID: CHEBI:69355
Term: casticin
Definition: A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii.
Chemical ID: MESH:C054133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkdcdecreases expressionISOPRKDC (Homo sapiens)6480464CTDcasticin results in decreased expression of PRKDC proteinPMID:29098808
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