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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319031
Species: Homo sapiens
RGD Object: Gene
Symbol: MTF1
Name: metal regulatory transcription factor 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTF1increases activityEXP 6480464CTDbisphenol A results in increased activity of MTF1 proteinPMID:36534918
MTF1decreases expressionISOMtf1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of MTF1 mRNAPMID:25181051
MTF1decreases expressionISOMtf1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of MTF1 mRNAPMID:26063408
MTF1decreases methylationISOMtf1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of MTF1 promoterPMID:27312807
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